Dr. Melisa Merdanovic

Research interests: 
  • Allosteric regulation in proteases
  • Protein quality control 
CoLab Biomed research keywords: 
Selected publications: 

Merdanovic M, Mönig T, Ehrmann M, Kaiser M. 2013. The diversity of allosteric regulation in proteases. ACS Chem Biol 8:19-26.

Merdanovic M, Clausen T, Kaiser M, Huber R and M. Ehrmann. 2011. Protein quality control in the bacterial periplasm. Annu. Rev. Microbiol. 65:149-168

Merdanovic M, Mamant N, Meltzer M, Poepsel S, Auckenthaler A, Melgaard R, Hauske P, Nagel-Steger L, Clarke AR, Kaiser M, Huber R, and M. Ehrmann. 2010. Determinants of structural and functional plasticity of a widely conserved protease chaperone complex. Nat. Struct. Mol. Biol. 17:837-43.

Meltzer M, Hasenbein S, Mamant N, Merdanovic M, Poepsel S, Hauske P, Kaiser M, Huber R, Krojer T, Clausen T, and M. Ehrmann. 2009. Structure, function and regulation of the conserved serine proteases DegP and DegS of E. coli. Res. Microbiol. 160:660-666.

Meltzer M, Hasenbein S, Hauske P, Kucz N, Merdanovic M, Grau S, Beil A, Jones D, Krojer T, Clausen T, Ehrmann M,* and M. Kaiser* (2008). Allosteric activation of HtrA protease DegP by stress signals in bacterial protein quality control. Angew Chem. Int. Ed. Engl. 47:1332-1334 *corresponding authors.

Hasenbein S, Merdanovic M, and M. Ehrmann (2007). Determinants of regulated proteolysis in signal transduction. Genes Dev. 21: 6-10.

Research group: 
Faculty of Biology
Centre for Medical Biotechnology (ZMB)
University of Duisburg-Essen
Contact information: 

+49 201 183 3832

Campus Essen
Room S03 S02 A50