Dr. Michael Meltzer

Research interests: 
  • Protein biogenesis and function
  • Protein folding and degradation
  • Protein quality control
CoLab Biomed research keywords: 
Selected publications: 

Weski J, Meltzer M, Spaan L, Mönig T, Oeljeklaus J, Hauske P, Vouilleme L, Volkmer R, Boisguerin P, Boyd D, Huber R, Kaiser M, Ehrmann M. 2012. Chemical biology approaches reveal conserved features of a C-terminal processing PDZ protease. Chembiochem. 13(3):402-8.

Stolze SC, Meltzer M, Ehrmann M, Kaiser M. 2012. Development of a solid-phase approach to the natural product class of Ahp containing cyclodepsipeptides. Eur. J. Org. Chem. 1616-1625.

Merdanovic M, Mamant N, Meltzer M, Poepsel S, Auckenthaler A, Melgaard R, Hauske P, Nagel-Steger L, Clarke AR, Kaiser M, Huber R, and M. Ehrmann. 2010. Determinants of structural and functional plasticity of a widely conserved protease chaperone complex. Nat. Struct. Mol. Biol. 17:837-43.

Hasenbein S, Meltzer M, Hauske P, Kaiser M, Huber R, Clausen T and M. Ehrmann. 2010. Conversion of a regulatory into a degradative protease. J. Mol. Biol. 397:957-966.

Meltzer M, Hasenbein S, Mamant N, Merdanovic M, Poepsel S, Hauske P, Kaiser M, Huber R, Krojer T, Clausen T, and M. Ehrmann. 2009. Structure, function and regulation of the conserved serine proteases DegP and DegS of E. coli. Res. Microbiol. 160:660-666.

Hauske P, Meltzer M, Ottmann C, Krojer T, Clausen T, Ehrmann M*, and M. Kaiser*. 2009 Selectivity profiling of DegP substrates and inhibitors. Bioorg. Med. Chem. 17:2920-2924, Cover article, *corresponding authors.

Hauske P, Ottmann C, Meltzer M, Ehrmann M, and M. Kaiser. 2008 Allosteric regulation of proteases. Chem. Biochem. 9:2920-2928.

Research group: 
Faculty of Biology
University of Duisburg-Essen
Contact information: 

+49 201 183 3831

Campus Essen
S03 S00 A44